Kristine Jepson has appeared in leading theaters internationally including the Metropolitan Opera, Teatro alla Scala, Royal Opera, Covent Garden, Theatre Royale de la Monnaie, Opera National de Paris, Royal Opera, Covent Garden, Bavarian State Opera, Hamburg State Opera, Flemish Opera, San Francisco Opera. Canadian Opera Company, Santa Fe Opera and many others.  Jepson has won special acclaim for roles such as Sesto in Mozart's La Clemenza di Tito, the Composer in Strauss's Ariadne auf Naxos and, Sister Helen in Dead Man Walking.  In December of 2000 Jepson sang her first performances as Octavian in Der Rosenkavalier at the Metropolitan Opera and was praised highly for her interpretation of this cornerstone of the mezzo repertoire.  She has since made her debuts at the Teatro alla Scala, Theatre de La Monnaie in Brussels, the Hamburg State Opera and Bavarian State Opera in Munich all as Octavian.

Kristine Jepson began the 2008/2009 season as Mere Marie in Dialogues des Carmelites in Oviedo before returning to Covent Garden as Nicklausse in Les Contes D’Hoffmann.  Ms. Jepson joined the Detroit Symphony Orchestra conducted by James Conlon for Das Lied von der Erde.  She will make her debut in Brazil in September of 2009 in Der Rosenkavalier in Sao Paulo and then appears with the Washington Opera in Ariadne. Jepson will return to the Hamburg State Opera for a new production of Das Gehege.  Later in the season she will sing her first performances of Fricka in Das Rheingold and Die Walkuere at the Deutsche Oper Berlin under Donald Runnicles.